{"product_id":"abm203595","title":"HLA-DPB1 Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eHLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57661566320980,"sku":"ABM203595","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57661566353748,"sku":"ABM203596","price":141.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-0fd94fa143bbb687ef96ae2b0934e3ce148a6aced7633e289437a574a94a5353.jpg?v=1792159145","url":"https:\/\/www.abmium.com\/de\/products\/abm203595","provider":"ABMIUM","version":"1.0","type":"link"}