{"product_id":"abm201845","title":"KIT Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell prolif- eration, apoptosis and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto- oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57661516120404,"sku":"ABM201845","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57661516153172,"sku":"ABM201846","price":141.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-6da546ffe691ada2b5c9d7c53dc8cdc9d8fe624b2076ed8b566a67aee33151fc.jpg?v=1792159122","url":"https:\/\/www.abmium.com\/de\/products\/abm201845","provider":"ABMIUM","version":"1.0","type":"link"}