{"product_id":"abm201643","title":"SMAD6 Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eAntagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD. Binds to regulatory elements in target promoter regions.Tissue specificity: Ubiquitous in various organs, with higher levels in lung. Isoform B is up-regulated in diseased heart tissue.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57661256565076,"sku":"ABM201643","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57661256597844,"sku":"ABM201644","price":141.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-de1b3821fd79a2f4ad530ee3e5ea968bbdfcbefab40f95ac7a5221eb2efcf06d.jpg?v=1792159026","url":"https:\/\/www.abmium.com\/de\/products\/abm201643","provider":"ABMIUM","version":"1.0","type":"link"}