{"product_id":"abm201351","title":"ARRB1 Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eMembers of arrestin\/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK\/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57660848177492,"sku":"ABM201351","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57660848210260,"sku":"ABM201352","price":141.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-8b3b718e07f7fb93c4e523f3315aa2808a1b7dd4506daf0e578d1b180e13941b.jpg?v=1792158948","url":"https:\/\/www.abmium.com\/de\/products\/abm201351","provider":"ABMIUM","version":"1.0","type":"link"}