{"product_id":"abm200241","title":"PA28 Gamma Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits| 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP\/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) o\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"50ul","offer_id":57661460152660,"sku":"ABM200241","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57661460185428,"sku":"ABM200242","price":192.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-05646d1c4b096399ba5c6e07d2b19c0990440ed6c948a8cb41a04fea12e3e06d.jpg?v=1792159005","url":"https:\/\/www.abmium.com\/de\/products\/abm200241","provider":"ABMIUM","version":"1.0","type":"link"}