{"product_id":"abm199733","title":"HIF-1 Beta\/ARNT Monoclonal Antibody(4C5)","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660954378580,"sku":"ABM199733","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660954411348,"sku":"ABM199734","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660954444116,"sku":"ABM199735","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-ee3c203fe3af96cc9639ba31dd411618ac56778a2fe549994a7d1bef71abacbc.jpg?v=1792159029","url":"https:\/\/www.abmium.com\/de\/products\/abm199733","provider":"ABMIUM","version":"1.0","type":"link"}