{"product_id":"abm197777","title":"XIAP(Phospho Ser87) Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660985278804,"sku":"ABM197777","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660985311572,"sku":"ABM197778","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660985344340,"sku":"ABM197779","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-e114b0b5a38887594463118cc7408869a0e9e1fee0e4228704cf8c8622c3ef1b.jpg?v=1792158992","url":"https:\/\/www.abmium.com\/de\/products\/abm197777","provider":"ABMIUM","version":"1.0","type":"link"}