{"product_id":"abm193646","title":"ACY1 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a cytosolic| homodimeric| zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group| and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1| a region reduced to homozygosity in small-cell lung cancer (SCLC)| and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart| and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency| a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription als\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57661497508180,"sku":"ABM193646","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57661497540948,"sku":"ABM193647","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57661497573716,"sku":"ABM193648","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-ae7eb45f6f9661e3c7422951505b281bf6070d3cac75aa6ab4a2ac4180cb3b9e.jpg?v=1792158962","url":"https:\/\/www.abmium.com\/de\/products\/abm193646","provider":"ABMIUM","version":"1.0","type":"link"}