{"product_id":"abm193643","title":"ACTN1 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins| including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells| the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions| where it is involved in binding actin to the membrane. In contrast| skeletal| cardiac| and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies| where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle| cytoskeletal| alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57661496000852,"sku":"ABM193643","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57661496033620,"sku":"ABM193644","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57661496066388,"sku":"ABM193645","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1ea4c7287cbfdf5088445786c5a5187a69f59f2a2d1db38ede993084a9fd9773.jpg?v=1792241051","url":"https:\/\/www.abmium.com\/de\/products\/abm193643","provider":"ABMIUM","version":"1.0","type":"link"}