{"product_id":"abm192989","title":"RPA32(Phospho Thr21) Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eRequired for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.,PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC\/DNA-PK in the presence of Ku and DNA, and by CDC2.,subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3\/RBT1. Interacts with TIPIN.,\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57661011099988,"sku":"ABM192989","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57661011132756,"sku":"ABM192990","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57661011165524,"sku":"ABM192991","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-9cc174cdc9f9081bf42369e594c2ba103ced85c9a8b5942343d3a9aefde00857.jpg?v=1792159041","url":"https:\/\/www.abmium.com\/de\/products\/abm192989","provider":"ABMIUM","version":"1.0","type":"link"}