{"product_id":"abm190694","title":"PKN3 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eCatalytic activity:ATP + a protein = ADP + a phosphoprotein.,The C1 domain does not bind the diacylglycerol (DAG).,enzyme regulation:Two specific sites, Thr-718 (activation loop of the kinase domain) and Thr-860 (turn motif), need to be phosphorylated for its full activation.,Contributes to invasiveness in malignant prostate cancer.,PTM:Autophosphorylated.,Belongs to the protein kinase superfamily. AGC Ser\/Thr protein kinase family. PKC subfamily.,Contains 1 AGC-kinase C-terminal domain.,Contains 1 protein kinase domain.,Contains 3 REM (Hr1) repeats.,subcellular location:Nuclear and perinuclear Golgi region.,tissue specificity:Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.,\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57661075718484,"sku":"ABM190694","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57661075751252,"sku":"ABM190695","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57661075784020,"sku":"ABM190696","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1ea4c7287cbfdf5088445786c5a5187a69f59f2a2d1db38ede993084a9fd9773.jpg?v=1792241051","url":"https:\/\/www.abmium.com\/de\/products\/abm190694","provider":"ABMIUM","version":"1.0","type":"link"}