{"product_id":"abm189536","title":"PACS1 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57661095379284,"sku":"ABM189536","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57661095412052,"sku":"ABM189537","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57661095444820,"sku":"ABM189538","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1ea4c7287cbfdf5088445786c5a5187a69f59f2a2d1db38ede993084a9fd9773.jpg?v=1792241051","url":"https:\/\/www.abmium.com\/de\/products\/abm189536","provider":"ABMIUM","version":"1.0","type":"link"}