{"product_id":"abm188273","title":"RN139 Rabbit Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum| and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL| as well as with COPS5\/JAB1| a protein responsible for the degradation of tumor suppressor CDKN1B\/P27KIP.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57661030629716,"sku":"ABM188273","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57661030662484,"sku":"ABM188274","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57661030695252,"sku":"ABM188275","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-b06ffc5f30eef37ea60d9220ab3214fcbe80446e87dd2b9fab65bf9d4df8031a.jpg?v=1792159035","url":"https:\/\/www.abmium.com\/de\/products\/abm188273","provider":"ABMIUM","version":"1.0","type":"link"}