{"product_id":"abm187928","title":"PRK1\/PRK2 Rabbit Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1\/PDK1) is reported to phosphorylate this kinase| which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57660799484244,"sku":"ABM187928","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660799517012,"sku":"ABM187929","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57660799549780,"sku":"ABM187930","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1ea4c7287cbfdf5088445786c5a5187a69f59f2a2d1db38ede993084a9fd9773.jpg?v=1792241051","url":"https:\/\/www.abmium.com\/de\/products\/abm187928","provider":"ABMIUM","version":"1.0","type":"link"}