{"product_id":"abm186701","title":"NDUV1 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple trans\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57660763275604,"sku":"ABM186701","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660763308372,"sku":"ABM186702","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57660763341140,"sku":"ABM186703","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1ea4c7287cbfdf5088445786c5a5187a69f59f2a2d1db38ede993084a9fd9773.jpg?v=1792241051","url":"https:\/\/www.abmium.com\/de\/products\/abm186701","provider":"ABMIUM","version":"1.0","type":"link"}