{"product_id":"abm185476","title":"MLK1\/2(Phospho Thr312\/266) Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eCatalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Homodimerization via the leucine zipper domains is required for autophosphorylation and subsequent activation.,Activates the JUN N-terminal pathway.,PTM:Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation. Thr-312 is likely to be the main autophosphorylation site.,Belongs to the protein kinase superfamily. STE Ser\/Thr protein kinase family. MAP kinase kinase kinase subfamily.,Contains 1 protein kinase domain.,Contains 1 SH3 domain.,subunit:Homodimer.,tissue specificity:Expressed in epithelial tumor cell lines of colonic, breast and esophageal origin.,\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660771860820,"sku":"ABM185476","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660771893588,"sku":"ABM185477","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660771926356,"sku":"ABM185478","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-e72efb83eb9445df9301500e4c9d5fb1243b2c909cda56eaaa42e9e218760937.jpg?v=1792159029","url":"https:\/\/www.abmium.com\/de\/products\/abm185476","provider":"ABMIUM","version":"1.0","type":"link"}