{"product_id":"abm184897","title":"MCM7 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1\/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57661198074196,"sku":"ABM184897","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57661198106964,"sku":"ABM184898","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57661198139732,"sku":"ABM184899","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-b95fb76657db640d78772daf69737b4948fdb37cabed39ec21a0d4e1820fcd1b.jpg?v=1792159000","url":"https:\/\/www.abmium.com\/de\/products\/abm184897","provider":"ABMIUM","version":"1.0","type":"link"}