{"product_id":"abm183916","title":"LAX1 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eNegatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.,induction:Up-regulated in T-cells following TCR engagement.,PTM:Phosphorylated on tyrosines by Syk, Lck or ZAP70 upon TCR or BCR activation; which leads to the recruitment of GRB2, PIK3R1 and GRAP2.,subunit:When phosphorylated, interacts with GRB2, PIK3R1 and GRAP2.,tissue specificity:Expressed in spleen, thymus, and peripheral blood leukocytes. Expressed in several B-, T-, NK and monocyte cell lines.,\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57661326852436,"sku":"ABM183916","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57661326885204,"sku":"ABM183917","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57661326917972,"sku":"ABM183918","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-0e410c6b41ad50d4f6f5a5521851e0da980cd10720a349d4a4f8ac08a54218f3.jpg?v=1792158962","url":"https:\/\/www.abmium.com\/de\/products\/abm183916","provider":"ABMIUM","version":"1.0","type":"link"}