{"product_id":"abm183586","title":"KPCI Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a member of the protein kinase C (PKC) family of serine\/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD\/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57661113205076,"sku":"ABM183586","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57661113237844,"sku":"ABM183587","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57661113270612,"sku":"ABM183588","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1ea4c7287cbfdf5088445786c5a5187a69f59f2a2d1db38ede993084a9fd9773.jpg?v=1792241051","url":"https:\/\/www.abmium.com\/de\/products\/abm183586","provider":"ABMIUM","version":"1.0","type":"link"}