{"product_id":"abm183343","title":"KDM3B Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003ecofactor:Binds 1 Fe(2+) ion per subunit.,Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.,Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.,miscellaneous:Its gene is located in the 5q region of the genome which is deleted in del(5q) interstitial deletion, a frequent deletion found in myeloid leukemias and myelodysplasias, suggesting that it may be a good candidate for the del(5q) tumor suppressor gene.,Belongs to the JHDM2 histone demethylase family.,Contains 1 JmjC domain.,tissue specificity:Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver.,\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57660950380884,"sku":"ABM183343","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660950413652,"sku":"ABM183344","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57660950446420,"sku":"ABM183345","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1ea4c7287cbfdf5088445786c5a5187a69f59f2a2d1db38ede993084a9fd9773.jpg?v=1792241051","url":"https:\/\/www.abmium.com\/de\/products\/abm183343","provider":"ABMIUM","version":"1.0","type":"link"}