{"product_id":"abm180852","title":"HBEGF Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eMay be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.,PTM:O-linked glycan attachment sites were determined by Edman degradation, O-glycanase digest suggests mucin-type glycosylation (done in HB-EGF purified from histiocytic lymphoma cell line U-937).,PTM:Several N-termini have been identified by direct sequencing. The forms with N-termini 63, 73 and 74 have been tested and found to be biologically active.,Contains 1 EGF-like domain.,subcellular location:Mature HB-EGF is released into the extracellular space and probably binds to a receptor.,\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659928576340,"sku":"ABM180852","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659928609108,"sku":"ABM180853","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659928641876,"sku":"ABM180854","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-90a4034c6aaa6945b2aefbb0b7015ccff42368633d0a62e1e677ba580016f2c5.jpg?v=1792159004","url":"https:\/\/www.abmium.com\/de\/products\/abm180852","provider":"ABMIUM","version":"1.0","type":"link"}