{"product_id":"abm180659","title":"GRPR Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eGastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659768406356,"sku":"ABM180659","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659768439124,"sku":"ABM180660","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659768471892,"sku":"ABM180661","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-ae227851b90da07609e90b14c54a759621a9fc23c4d94df7f9f736865d2295d4.jpg?v=1792158993","url":"https:\/\/www.abmium.com\/de\/products\/abm180659","provider":"ABMIUM","version":"1.0","type":"link"}