{"product_id":"abm179494","title":"DUS7 Rabbit Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eDual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine\/threonine residues. DUSP7 belongs to a class of DUSPs| designated MKPs| that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795)| JNK (see MIM 601158)| and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes| including cellular proliferation| apoptosis| differentiation| and stress responses (summary by Patterson et al.| 2009\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659787903316,"sku":"ABM179494","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659787936084,"sku":"ABM179495","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659787968852,"sku":"ABM179496","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-cb1ef5f831abe3bcad4c57046aba59e058769d89b187ada4cb45d9ee7628a9ed.jpg?v=1792158874","url":"https:\/\/www.abmium.com\/de\/products\/abm179494","provider":"ABMIUM","version":"1.0","type":"link"}