{"product_id":"abm178927","title":"TRAP220 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by MED1 (mediator complex subunit 1) is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. Thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660332802388,"sku":"ABM178927","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660332835156,"sku":"ABM178928","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660332867924,"sku":"ABM178929","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-4ed7937fa065944bc4c6dfbe218e6e48a279af85e5fbe97f922fbe57e1149411.jpg?v=1792158823","url":"https:\/\/www.abmium.com\/de\/products\/abm178927","provider":"ABMIUM","version":"1.0","type":"link"}