{"product_id":"abm176647","title":"SMAP45 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation\/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 3 encoded by HDAC3 belongs to the histone deacetylase\/acuc\/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660320088404,"sku":"ABM176647","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660320121172,"sku":"ABM176648","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660320153940,"sku":"ABM176649","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-eebff3586dbf8b26ce0ce8e365f2ee70534dbd19501dcb53c229a0d355c6ab16.jpg?v=1792158897","url":"https:\/\/www.abmium.com\/de\/products\/abm176647","provider":"ABMIUM","version":"1.0","type":"link"}