{"product_id":"abm175780","title":"Crk II(Phospho Tyr221) Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660673589588,"sku":"ABM175780","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660673622356,"sku":"ABM175781","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660673655124,"sku":"ABM175782","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-7907071c6496fe0614e8ec2b971285e6c68719504ae30c7d97ea7ad133949b40.jpg?v=1792158813","url":"https:\/\/www.abmium.com\/de\/products\/abm175780","provider":"ABMIUM","version":"1.0","type":"link"}