{"product_id":"abm172261","title":"c-Myc(Phospho Thr58) Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659768111444,"sku":"ABM172261","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659768144212,"sku":"ABM172262","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659768176980,"sku":"ABM172263","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-7f93c213ca7be77b30c1480e1588c85438179e664b6aae138b720e651f0fd52a.jpg?v=1792158839","url":"https:\/\/www.abmium.com\/de\/products\/abm172261","provider":"ABMIUM","version":"1.0","type":"link"}