{"product_id":"abm172243","title":"Caspase-10 Rabbit Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits| large and small| that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7| and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome| non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57659753333076,"sku":"ABM172243","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659753365844,"sku":"ABM172244","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57659753398612,"sku":"ABM172245","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1ea4c7287cbfdf5088445786c5a5187a69f59f2a2d1db38ede993084a9fd9773.jpg?v=1792241051","url":"https:\/\/www.abmium.com\/de\/products\/abm172243","provider":"ABMIUM","version":"1.0","type":"link"}