{"product_id":"abm165796","title":"SF3B1(Phospho-Thr313) Rabbit Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b| together with splicing factor 3a and a 12S RNA unit| forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b\/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical| tandem HEAT repeats that form rod-like| helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57660441559380,"sku":"ABM165796","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660441592148,"sku":"ABM165797","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57660441624916,"sku":"ABM165798","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-1ea4c7287cbfdf5088445786c5a5187a69f59f2a2d1db38ede993084a9fd9773.jpg?v=1792241051","url":"https:\/\/www.abmium.com\/de\/products\/abm165796","provider":"ABMIUM","version":"1.0","type":"link"}