{"product_id":"abm165109","title":"IL-22 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eIL-10-related T cell-derived inducible factor (IL-22, also known as IL-TIF) is a cytokine that was originally identified in mouse as an IL-9 inducible gene in T cells and mast cells and shows 22% amino acid identity with IL-10. Additionally, IL-22 is induced by IL-9 in thymic lymphomas and by lectins in freshly isolated splenocytes. IL-22 is found in both the thymus and brain, which suggests that the role of this factor is not restricted to the immune system. IL-22 is a ligand for CRF2-4, a member of the class II cytokine receptor family. In contrast to IL-10, IL-22 does not inhibit the production of proinflammatory cytokines by monocytes in response to lipopolysaccharide nor does it impact IL-10 function on monocytes, but it has modest inhibitory effects on IL-4 production from Th2 T cells.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659819753812,"sku":"ABM165109","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659819786580,"sku":"ABM165110","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659819819348,"sku":"ABM165111","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-f85c26398c6a783e21cd3fe7f6a1162493ee8acb3a7dd044009651629434f0af.jpg?v=1792158812","url":"https:\/\/www.abmium.com\/de\/products\/abm165109","provider":"ABMIUM","version":"1.0","type":"link"}