{"product_id":"abm163849","title":"PCDC1 Rabbit Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene is a member of the protocadherin alpha gene cluster| one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons| or variable exons| are followed by downstream C-terminal exons| or constant exons| which are shared by all genes in the cluster. The large| uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57659753234772,"sku":"ABM163849","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659753267540,"sku":"ABM163850","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57659753300308,"sku":"ABM163851","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-722252a0bbc55e538d184ad7d94f98c80a7cb8e34a468be6994b2c82795b85cc.jpg?v=1792157361","url":"https:\/\/www.abmium.com\/de\/products\/abm163849","provider":"ABMIUM","version":"1.0","type":"link"}