{"product_id":"abm160360","title":"eIF3Epsilon Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eComponent of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.Deubiquitinates activated NOTCH1, promoting its nuclear import, thereby acting as a positive regulator of Notch signaling.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659873001812,"sku":"ABM160360","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659873034580,"sku":"ABM160361","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659873067348,"sku":"ABM160362","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-4f3b010d6a8d28a08f64f83aa06304584b9eb572d8870bb70a21cc62bd15b919.jpg?v=1792157316","url":"https:\/\/www.abmium.com\/de\/products\/abm160360","provider":"ABMIUM","version":"1.0","type":"link"}