{"product_id":"abm159226","title":"DCC Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eDCC encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein DCC netrin 1 receptor localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659855569236,"sku":"ABM159226","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659855602004,"sku":"ABM159227","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659855634772,"sku":"ABM159228","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-884a06c63d4f9f21c8c010b38e318c848d162e66e4dad2a77c112dc797119e9f.jpg?v=1792157302","url":"https:\/\/www.abmium.com\/de\/products\/abm159226","provider":"ABMIUM","version":"1.0","type":"link"}