{"product_id":"abm157477","title":"Cleaved-Integrin  AlphaV HC (K889) Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe product of ITGAV belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660393259348,"sku":"ABM157477","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660393292116,"sku":"ABM157478","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660393324884,"sku":"ABM157479","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-64d02a282398175254bf03522eddc6cf4a52a4523e82e65acdbe4fb724ff948c.jpg?v=1792157358","url":"https:\/\/www.abmium.com\/de\/products\/abm157477","provider":"ABMIUM","version":"1.0","type":"link"}