{"product_id":"abm156747","title":"Tak1(Phospho Thr187) Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene is a member of the serine\/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP)| and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1| this protein forms a kinase complex including TRAF6| MAP3K7P1\/TAB1 and MAP3K7P2\/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8\/JNK| MAP2K4\/MKK4| and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659844755796,"sku":"ABM156747","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659844788564,"sku":"ABM156748","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659844821332,"sku":"ABM156749","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-42792802d69c66e2955bdcd7ab8ab948e12b46d8be80399a9e429054012db334.jpg?v=1792157388","url":"https:\/\/www.abmium.com\/de\/products\/abm156747","provider":"ABMIUM","version":"1.0","type":"link"}