{"product_id":"abm153840","title":"ATF-7 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eEukaryotic gene transcription is regulated by sequence-specific transcription factors that bind modular cis acting promoter and enhancer elements. The ATF\/CREB transcription factor family binds the palindromic cAMP response element (CRE) octanucleotide TGACGTCA. The best characterized members of this gene family include CREB-1, CREB-2 (also designated ATF-4), CRE-BPa, LZIP (also designated CREB3 and Luman), CREM-1, CREM-2, ATF-1, ATF-2, ATF-3, ATF-5, ATF-6 and ATF-7. This family of proteins contain highly divergent N-terminal domains, but share a C-terminal leucine zipper for dimerization and DNA binding. ATF-5 (ATFx), which can localize to the cytoplasm or the nucleus, binds DNA as a dimer. It interacts with CCND3 and PTP4A1.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660517548372,"sku":"ABM153840","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660517581140,"sku":"ABM153841","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660517613908,"sku":"ABM153842","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-2c65a17e80c393b6a9e10a200e55f2f86a27782ead4023f842b793aa28cae9b5.jpg?v=1792157326","url":"https:\/\/www.abmium.com\/de\/products\/abm153840","provider":"ABMIUM","version":"1.0","type":"link"}