{"product_id":"abm153591","title":"ARP Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eMesencephalic astrocyte-derived neurotrophic factor encoded by MANF is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660281028948,"sku":"ABM153591","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660281061716,"sku":"ABM153592","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660281094484,"sku":"ABM153593","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-515a21c202915285fdbc008e1a03c7e2a3451ab95f6bdd69785ccc80ef6c4b1c.jpg?v=1792157297","url":"https:\/\/www.abmium.com\/de\/products\/abm153591","provider":"ABMIUM","version":"1.0","type":"link"}