{"product_id":"abm152610","title":"CCR5 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemok\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100ul","offer_id":57660487631188,"sku":"ABM152610","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660487663956,"sku":"ABM152611","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"20ul","offer_id":57660487696724,"sku":"ABM152612","price":69.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-a9f78047461f623245272fb15a3ee720f0cbe0f93761cfc2dd6137b6091a86cb.jpg?v=1792157342","url":"https:\/\/www.abmium.com\/de\/products\/abm152610","provider":"ABMIUM","version":"1.0","type":"link"}