{"product_id":"elk-es10819-nuak2-rabbit-pab","title":"NUAK2 rabbit pAb","description":"\u003cp\u003eNUAK2 rabbit pAb is a research-use antibody from ELK Biotechnology for studying NUAK2 in WB, ELISA workflows with listed reactivity for Human, Rat, Mouse. Specifications and supporting documents below should be reviewed when planning the experiment.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003ecatalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-208 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells.,PTM:Autophosphorylated in vitro.,similarity:Belongs to the protein kinase superfamily. CAMK Ser\/Thr protein kinase family. SNF1 subfamily.,similarity:Contains 1 protein kinase domain.,\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eNUAK2 Polyclonal Antibody detects endogenous levels of protein.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56184971297108,"sku":"ABM102927","price":220.0,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56184971329876,"sku":"ABM93063","price":132.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/3_683eeba3-2270-4dc3-bc2f-4a5a4ac99d4a.png?v=1783151173","url":"https:\/\/www.abmium.com\/da\/products\/elk-es10819-nuak2-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}