{"product_id":"anti-shp2-ptpn11-antibody-picoband-monoclonal-2e6-m00150-2","title":"Anti-SHP2\/PTPN11 Antibody Picoband® (monoclonal, 2E6","description":"\u003cp\u003eAnti-SHP2\/PTPN11 Antibody Picoband® (monoclonal, 2E6 is a research-use antibody from Boster Bio for studying Tyrosine-protein phosphatase non-receptor type 11 in ELISA, Flow Cytometry, IF\/ICC, IHC, IHC-P, WB workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.\u003c\/p\u003e\nBoster Bio Anti-SHP2\/PTPN11 Antibody Picoband® (monoclonal, 2E6) catalog # M00150-2. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.\u003cp\u003ePTPN11 (Tyrosine-protein phosphatase non-receptor type 11), also known as protein-tyrosine phosphatase 1D (PTP-1D), protein-tyrosine phosphatase 2C (PTP-2C), TYROSINE PHOSPHATASE SHP2 (SHP2), BPTP3, SH-PTP2, SHP-2, SH-PTP3, is an enzyme that in humans is encoded by the PTPN11 gene. PTPN11 is a member of the protein tyrosine phosphatase (PTP) family. The open reading frame consists of 1,779 nucleotides potentially encoding a protein of 593 amino acids with a predicted molecular mass of 68 kD. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.\u003c\/p\u003e\u003ch3\u003eProduct information\u003c\/h3\u003e","brand":"Boster Bio","offers":[{"title":"Unconjugated \/ 100 μg\/vial","offer_id":56040135033172,"sku":"ABM22529-1","price":328.0,"currency_code":"GBP","in_stock":true},{"title":"Biotin \/ 100 μg\/vial","offer_id":56040135065940,"sku":"ABM22529-2","price":505.0,"currency_code":"GBP","in_stock":true},{"title":"Cy3 \/ 100 μg\/vial","offer_id":56040135098708,"sku":"ABM22529-3","price":505.0,"currency_code":"GBP","in_stock":true},{"title":"Fluoro488 \/ 100 μg\/vial","offer_id":56040135131476,"sku":"ABM22529-4","price":505.0,"currency_code":"GBP","in_stock":true},{"title":"Fluoro550 \/ 100 μg\/vial","offer_id":56040135164244,"sku":"ABM22529-5","price":505.0,"currency_code":"GBP","in_stock":true},{"title":"Fluoro594 \/ 100 μg\/vial","offer_id":56040135197012,"sku":"ABM22529-6","price":505.0,"currency_code":"GBP","in_stock":true},{"title":"FITC \/ 100 μg\/vial","offer_id":56040135229780,"sku":"ABM22529-7","price":505.0,"currency_code":"GBP","in_stock":true},{"title":"HRP \/ 100 μg\/vial","offer_id":56040135262548,"sku":"ABM22529-8","price":505.0,"currency_code":"GBP","in_stock":true},{"title":"APC \/ 100 μg\/vial","offer_id":56040135295316,"sku":"ABM22529-9","price":726.0,"currency_code":"GBP","in_stock":true},{"title":"PE \/ 100 μg\/vial","offer_id":56040135328084,"sku":"ABM22529-10","price":726.0,"currency_code":"GBP","in_stock":true},{"title":"Fluoro647 \/ 100 μg\/vial","offer_id":56040135360852,"sku":"ABM22529-11","price":593.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/m00150-2-ptpn11-primary-antibodies-ihc-testing-2.jpg?v=1781645481","url":"https:\/\/www.abmium.com\/da\/products\/anti-shp2-ptpn11-antibody-picoband-monoclonal-2e6-m00150-2","provider":"ABMIUM","version":"1.0","type":"link"}