{"product_id":"human-mmp13-collagenase-3-elisa-kit-picokine-ek0468","title":"Human MMP13\/Collagenase 3 ELISA Kit PicoKine®","description":"\u003cp\u003eHuman MMP13\/Collagenase 3 ELISA Kit PicoKine® is a research-use ELISA kit from Boster Bio for measuring Collagenase 3 in Cell culture supernatant, serum and plasma ( heparin). samples from Human. Use the listed assay range, sample guidance and protocol documents to assess suitability for the intended study.\u003c\/p\u003e\nHuman MMP13 ELISA Kit PicoKine® (96 Tests). Quantitate Human MMP13 in cell culture supernatants, serum and plasma ( heparin). Sensitivity: 5pg\/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.\u003cp\u003eCollagenase 3 is an enzyme that in humans is encoded by the MMP13 gene. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. The expression of MMP13 in osteoarthritic cartilage and its activity against type II collagen indicates that the enzyme plays a significant role in cartilage collagen degradation and must, therefore, form part of a complex target for proposed therapeutic interventions based on collagenase inhibition. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.\u003c\/p\u003e\u003ch3\u003eProduct information\u003c\/h3\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":56042578641236,"sku":"ABM32457","price":442.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ek0468_1.png?v=1781660001","url":"https:\/\/www.abmium.com\/cy\/products\/human-mmp13-collagenase-3-elisa-kit-picokine-ek0468","provider":"ABMIUM","version":"1.0","type":"link"}