{"product_id":"elk-em1052-p53-mouse-mab","title":"p53 Mouse mAb","description":"\u003cp\u003ep53 Mouse mAb is a research-use antibody from ELK Biotechnology for studying p53 in WB, IHC, IF workflows with listed reactivity for Human. Specifications and supporting documents below should be reviewed when planning the experiment.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003ep53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro.\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of 293T, with p53 mAb diluted at 1) 1:1,000 2) 1:2,000 | IHC staining of Human colon cancer tissue paraffin-embedded with p53 mouse mAb（6C4）diluted at 1:200. | IF analysis of Hela with EM1052(Left) and DAPI (Right) diluted at 1:100.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56184862474580,"sku":"ABM102275","price":220.0,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56184862507348,"sku":"ABM92411","price":132.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/EM1052-c-1.jpg?v=1782026748","url":"https:\/\/www.abmium.com\/cy\/products\/elk-em1052-p53-mouse-mab","provider":"ABMIUM","version":"1.0","type":"link"}