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MAP2K1

mitogen-activated protein kinase kinase 1

MAP2K1 identifies mitogen-activated protein kinase kinase 1 in Homo sapiens (Human). This target record connects NCBI Gene 5604, UniProtKB Q02750 and related ABMIUM catalogue products.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene5604 UniProtQ02750

ABMIUM research catalogue

Research Products

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Alternative names and identifiers

Names used across publications, databases and supplier catalogues.

Dual specificity mitogen-activated protein kinase kinase 1MEK1CFC3MAPKK1MELMKK1MP2K1PRKMK1

Biological function

Dual specificity mitogen-activated protein kinase kinase 1 (MAP2K1; MEK1/MKK1) is a dual-specificity kinase in the RAS-RAF-MEK-ERK pathway. It phosphorylates and activates ERK1/ERK2, coupling upstream growth-factor signals to cellular proliferation, differentiation and survival programs.

Research context

MAP2K1 (MEK1/MKK1) is studied in RAS-RAF-MEK-ERK signalling, growth-factor responses, proliferation, differentiation and cancer biology. Use the catalogue filters below to compare ABMIUM MAP2K1 reagents and confirm product-level suitability before use.