ABMIUM target intelligence

IL33

interleukin 33

IL33 identifies interleukin 33 in Homo sapiens (Human). This target record connects NCBI Gene 90865, UniProtKB O95760 and related ABMIUM catalogue products.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene90865 UniProtO95760

ABMIUM research catalogue

Research Products

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Alternative names and identifiers

Names used across publications, databases and supplier catalogues.

Interleukin-33C9orf26DVS27IL1F11NF-HEVNFEHEV9230117N10RikRGD1311155

Biological function

IL33 is an IL-1 family cytokine that signals through IL1RL1/ST2, activating NF-kappa-B and MAPK pathways. It promotes type 2 immune responses and can activate mast cells, basophils, eosinophils and natural killer cells.

Research context

IL33 is widely studied in type 2 immunity, allergy, inflammation, epithelial stress signalling and innate immune-cell activation. Reagent selection should consider species, processing state, sample type, assay format, application and supporting validation.