ABMIUM target intelligence
erb-b2 receptor tyrosine kinase 2
ERBB2 identifies erb-b2 receptor tyrosine kinase 2 in Homo sapiens (Human). This target record connects NCBI Gene 2064, UniProtKB P04626 and related ABMIUM catalogue products.
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Names used across publications, databases and supplier catalogues.
ERBB2 (HER2) is a receptor tyrosine kinase in the EGFR/ERBB family. It has no known direct activating ligand and acts as a preferred heterodimerisation partner for other ligand-bound ERBB receptors, amplifying downstream signalling controlling cell proliferation, survival and differentiation.
ERBB2 is widely studied in receptor tyrosine-kinase signalling, epithelial biology, cell proliferation and cancer models. Reagent selection should consider expression level, phosphorylation or activation state, species, sample type, assay format, application and supporting validation.