ABMIUM target intelligence
bone marrow stromal cell antigen 1
BST1 (bone marrow stromal cell antigen 1), also known as CD157, is a GPI-anchored ectoenzyme whose reviewed protein is ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2.
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Names used across publications, databases and supplier catalogues.
BST1/CD157 can catalyse formation of cyclic ADP-ribose from NAD+ and hydrolyse cyclic ADP-ribose to ADP-ribose. Cyclic ADP-ribose functions as a calcium-mobilizing second messenger, while BST1 has also been implicated in supporting pre-B-cell growth in stromal-cell contexts.
BST1/CD157 is studied in extracellular NAD metabolism, cyclic ADP-ribose and calcium-signalling biology, stromal-cell support of immune-cell development, and CD157 cell-surface biology. Product-level species and application validation should be checked before experimental use.