ABMIUM target intelligence
arginase 2
Arginase 2 (ARG2; arginase II) is the mitochondrial type-II arginase that hydrolyses L-arginine to ornithine and urea. This catalogue-backed ABMIUM record links human ARG2 (NCBI Gene 384; UniProt P78540) to research reagents for arginine-metabolism studies.
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Names used across publications, databases and supplier catalogues.
Arginase 2 (ARG2) catalyses the hydrolysis of L-arginine to L-ornithine and urea in mitochondria. By consuming arginine and generating ornithine, it connects mitochondrial arginine handling with nitrogen metabolism and pathways that influence nitric-oxide and polyamine availability.
ARG2 is studied in mitochondrial and extrahepatic arginine metabolism, nitric-oxide biology, polyamine metabolism and metabolic regulation, particularly in kidney and other non-hepatic tissues. Review species, assay format, application and product-level validation for each linked ABMIUM reagent.