ABMIUM target intelligence
activity regulated cytoskeleton associated protein
Activity regulated cytoskeleton associated protein (ARC; Arc/Arg3.1) is an activity-induced neuronal protein and master regulator of synaptic plasticity. This catalogue-backed ABMIUM record links human ARC (NCBI Gene 23237; UniProt Q7LC44) to research reagents.
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Names used across publications, databases and supplier catalogues.
ARC is rapidly induced by neuronal activity and supports protein-synthesis-dependent forms of long-term potentiation and depression, receptor trafficking and long-term memory. ARC can self-assemble into virus-like capsids that package RNA and participate in intercellular RNA transfer.
ARC/Arg3.1 is studied in activity-dependent neuronal signalling, synaptic plasticity, postsynaptic receptor trafficking, memory mechanisms and extracellular RNA transfer. Review species, assay format, application and product-level validation for each linked ABMIUM reagent.