ABMIUM target intelligence
angiopoietin 2
ANGPT2 identifies angiopoietin 2 in Homo sapiens (Human). This target record connects NCBI Gene 285, UniProtKB O15123 and related ABMIUM catalogue products.
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Names used across publications, databases and supplier catalogues.
ANGPT2 (angiopoietin-2) is a secreted vascular ligand that binds TEK/TIE2 and competes with ANGPT1, modulating Tie2 signaling and endothelial stability. Its effects are context-dependent: it can support vascular regression without pro-angiogenic cues and facilitate endothelial migration and proliferation in the presence of VEGF.
ANGPT2 is widely studied in angiogenesis, vascular remodeling, endothelial activation, inflammation and lymphangiogenesis. ABMIUM research products associated with ANGPT2 can support studies of expression and extracellular vascular signaling; confirm species, application, sample type and product-level validation before use.