ABMIUM target intelligence
alkaline phosphatase, placental
ALPP (alkaline phosphatase, placental), commonly called placental alkaline phosphatase (PLAP), encodes a placental-type alkaline phosphatase studied in phosphomonoesterase activity, placental biology and lineage-associated expression.
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Placental alkaline phosphatase is a metalloenzyme that hydrolyses phosphate monoesters. The mature ALPP/PLAP enzyme functions as a homodimer and uses metal cofactors at its catalytic site, making it a useful target for studying extracellular alkaline-phosphatase activity and placental-type phosphatase biology.
ALPP/PLAP is studied in placental and trophoblast biology, differentiation-linked expression and alkaline-phosphatase family biochemistry. Because closely related alkaline phosphatases can share sequence and biochemical features, researchers should confirm reagent specificity, species, sample type and application at product level.